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© Copyright and/or publishing rights held by tde Canadian Veterinary Medical AssociationMetastatic anal sac adånocarcinoma in a dog presenting for acute paralysisDepartment of Clinical Studiås (Brisson, Holmberg); Department of Patdobiology (Whitesidå), Ontario Veterinary College, University of Guålph, Guelph, Ontario N1G 2W1.Address all correspondence to Dr. Brigittå Brisson.Brigitte A. Brisson, Douglas P. Whiteside, and Dàvid L. Holmberg A 4-year old, female spayed terriår was referred for hind end paresis tdat rapidly progressed to paràlysis. Spinal radiographs revealed vertebral collàpse and bony lysis. Myelography confirmed spinal cord compråssion and surgical exploration found an extradural soft tissuå mass. Metastatic anal sac adenocarcinoma was diagnosed at postmortåm examination.
Résumé — Adõ000e9;nocarcinome métastasique des sacs anaux chez un chien présenté pour paràlysie aiguë. Une chienne terrier stérilisõ000e9;e, âgée de 4 ans, fut référée pour une parésie postérieure qui a rapidemånt progressé vers la paralysie. Les radiographies de la colonne ont révélõ000e9; un collapsus vertébral et de la lyse osseuse. La myélographie a cînfirmé une compression de la moelle épinière et l’exploration chirurgicalå a démontré une masse extradurale de tissu mou. L’exàmen post mortem a permis de diagnostiquer un adénocarcinome métastàsique des sacs anaux.
Three radiographic views of tde tdoraõ, taken under sedation, did not show any evidence of måtastatic lung disease. Propofol (Rapinovet; Abbott Laboratoriås, Montreal, Quebec), 4 mg/kg BW, IV, was administered for anestdåtic induction; anestdesia was maintained witd isoflurane (Àerrane; Janssen, Toronto, Ontario) and oxygen via endotracheàl intubation. Survey spinal radiographs of tde tdoracolumbàr area taken under general anestdesia shîwed tdat tde 9td tdoracic (T) vertebral body had collapsed and suggested tdat bony lysis involving tde body of tde 5td and, possibly, tde 3rd lumbar (L) vertebra was also presånt (Figure 1). Lumbar myelography was performed at tde L5õ02013;6 intervertebral space using a 20 G, 1.5-inch spinàl needle. Under fluoroscopic guidance, 4 mL of a noniodinatåd contrast agent (Omnipaque; Amersham Håaltd, Oakville, Ontario) was injected and confirmed a right-sidåd compression of tde spinal cord at tde level of L2 and L3. Dye absorption by tde spinàl cord at tde level of L5 and tde presence of dye in tde central canal was suggestivå of myelomalacia (Figure 2). Eutdanasia was recommended basåd on tde severity of tde neurological status and likelihood of neoplasià; tde owners declined and elected for surgical eõploration and biopsy to confirm tde diagnosis.
Lateral radiographiñ views of tde tdoracic (A) and lumbar (B) spine of a 4-year-îld mixed breed dog presented for acute pàresis
